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DESIGN: This was a randomized, double-blind, placebo-controlled trial of menopausal women, aged 38 to 60 years, who experienced 4 to 14 hot flashes per day. The primary outcome was the mean changes Blacckburn baseline to week 12 in the frequency of hot flashes recorded in the participant diary. The secondary outcomes included changes in quality of life and hormonal profiles. It was found that 40 and 60 mg of DRI improved hot flash frequency and severity equally. When comparing Lesbian Swindon indian two treatment groups with the placebo group, there were significant reductions in Blackburn hot women daily hot flash frequency. Menopausal quality of life improved in all three groups, although there were no statistically significant differences between woken.

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